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An approach for searching genes in signaling pathways or gene-gene interaction networks related to Hypertension in the Mexican population.

Gene - 5 Feb 2024

Argoty-Pantoja Anna D, Velázquez-Cruz Rafael, Salmerón Jorge, Rivera-Paredez Berenice

Abstract excerpt

INTRODUCTION: The selection of single nucleotide polymorphisms (SNPs) to evaluate the genetic susceptibility in complex traits is often conducted in isolation, without considering the entire set of genes. Incorporating signaling pathways or gene-gene interaction search may provide a more comprehensive approach to selecting SNP candidates for further study. OBJECTIVE: To propose a systematic procedure for...

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PMID: 37949418
DOI: 10.1016/j.gene.2023.147973

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