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Article

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Nature human behaviour - 1 Feb 2024

Li Wenqiang, Chen Rui, Feng Laipeng, Dang Xinglun, Liu Jiewei, Chen Tengfei, Yang Jinfeng, Su Xi, Lv Luxian, Li Tao, Zhang Zhijun, Luo Xiong-Jian

Abstract excerpt

Anxiety disorders are the most prevalent mental disorders. However, the genetic etiology of anxiety disorders remains largely unknown. Here we conducted a genome-wide meta-analysis on anxiety disorders by including 74,973 (28,392 proxy) cases and 400,243 (146,771 proxy) controls. We identified 14 risk loci, including 10 new associations near CNTNAP5, MAP2, RAB9BP1, BTN1A1, PRR16, PCLO, PTPRD, FARP1, CDH2 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37945807
DOI: 10.1038/s41562-023-01746-y

Genes

CTNND1
RAB27B
PCLO
BTN1A1
BTN3A2
CDH2
CNTNAP5
FARP1
MAP2
PRR16
PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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