Article
Single-cell landscape of peripheral immune response in patients with anti-melanoma differentiation–associated gene 5 dermatomyositis
6 Nov 2023
Abstract excerpt
OBJECTIVE: Anti-melanoma differentiation-associated gene 5 (Anti-MDA5)-positive DM is a rare but life-threatening autoimmune disorder that is associated with a high risk of developing rapidly progressive interstitial lung disease. Current empirical therapies offer limited benefit in terms of patient survival, as little is known about the aetiology of anti-MDA5 DM. To best understand its immune landscape, we...
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