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Pathogenesis of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis: A Concise Review With an Emphasis on Type I Interferon System

24 Jan 2022

Abstract excerpt

Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+DM) is typically characterized by cutaneous manifestations, amyopathic or hypomyopathic muscle involvement, and a high incidence of rapid progressive interstitial lung disease (RP-ILD). However, the exact etiology and pathogenesis of this condition has yet to be fully elucidated. Melanoma differentiation-associated gene 5...

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PMID: 35141258
DOI: 10.3389/fmed.2021.833114

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