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Article

Aberrant activation of the type I interferon system may contribute to the pathogenesis of anti‐melanoma differentiation‐associated gene 5 dermatomyositis

27 Jun 2018

Abstract excerpt

Anti‐melanoma differentiation‐associated gene 5 (MDA5) dermatomyositis (DM) is a distinctive subtype of DM that carries a significant risk of interstitial lung disease (ILD). The mechanisms remain elusive. To explore the role of the type I interferon (IFN) system in the pathogenesis of anti‐MDA5 DM. Twenty patients with anti‐MDA5 DM were studied and compared with patients with anti‐aminoacyl‐tRNA synthetase (ARS)...

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Share to Inflammatory Myopathies and Dermatomyositis
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PMID: 29947075
DOI: 10.1111/bjd.16917

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