Article
A Developmentally Informed Study of Sleep and Circadian Polygenic Scores in Adolescence.
JAMA psychiatry - 1 May 2026
Lewis Katie J S, Martin Joanna, Heron Jon, Riglin Lucy, Rice Frances, O'Donovan Michael C, Gregory Alice M
Abstract excerpt
Importance: Genome-wide association studies (GWAS) of sleep and circadian phenotypes have identified common genetic variants associated with these phenotypes in adults, but the relevance of these findings for younger age groups is unclear. It is important to determine whether genetic variants identified in these studies also index sleep phenotypes in adolescence, a time where sleep problems often emerge and have...
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