Article
Sleep disturbances in ADHD: investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes.
European child & adolescent psychiatry - 1 Jul 2023
Lewis Katie J S, Martin Joanna, Gregory Alice M, Anney Richard, Thapar Anita, Langley Kate
Abstract excerpt
Sleep disturbances are common in attention deficit hyperactivity disorder (ADHD) and associated with poor outcomes. We tested whether, in children with ADHD, (1) polygenic liability for sleep phenotypes is over- or under-transmitted from parents, (2) this liability is linked to comorbid sleep disturbances, and (3) ADHD genetic risk is associated with comorbid sleep disturbances. We derived polygenic scores (PGS)...
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