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Article

Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants.

JAMA psychiatry - 1 Mar 2020

Lewis Katie J S, Richards Alexander, Karlsson Robert, Leonenko Ganna, Jones Samuel E, Jones Hannah J, Gordon-Smith Katherine, Forty Liz, Escott-Price Valentina, Owen Michael J, Weedon Michael N, Jones Lisa, Craddock Nick, Jones Ian, Landén Mikael, O'Donovan Michael C, Di Florio Arianna

Abstract excerpt

Importance: Insomnia, hypersomnia, and an evening chronotype are common in individuals with bipolar disorder (BD), but whether this reflects shared genetic liability is unclear. Stratifying by BD subtypes could elucidate this association and inform sleep and BD research. Objective: To assess whether polygenic risk scores (PRSs) for sleep traits are associated with BD subtypes I and II. Design, Setting, and...

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Identifiers

PMID: 31751445
DOI: 10.1001/jamapsychiatry.2019.4079
PMCID: PMC6902167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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