Article
The role of mitochondria in stem cell fate and aging.
Development (Cambridge, England) - 13 Apr 2018
Zhang Hongbo, Menzies Keir J, Auwerx Johan
Abstract excerpt
The importance of mitochondria in energy metabolism, signal transduction and aging in post-mitotic tissues has been well established. Recently, the crucial role of mitochondrial-linked signaling in stem cell function has come to light and the importance of mitochondria in mediating stem cell activity is becoming increasingly recognized. Despite the fact that many stem cells exhibit low mitochondrial content and a...
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