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Article

Diagnostic Outcomes of Concurrent DNA and RNA Sequencing in Individuals Undergoing Hereditary Cancer Testing.

JAMA oncology - 1 Feb 2024

Horton Carolyn, Hoang Lily, Zimmermann Heather, Young Colin, Grzybowski Jessica, Durda Kate, Vuong Huy, Burks David, Cass Ashley, LaDuca Holly, Richardson Marcy E, Harrison Steven, Chao Elizabeth C, Karam Rachid

Abstract excerpt

Importance: Personalized surveillance, prophylaxis, and cancer treatment options for individuals with hereditary cancer predisposition are informed by results of germline genetic testing. Improvements to genomic technology, such as the availability of RNA sequencing, may increase identification of individuals eligible for personalized interventions by improving the accuracy and yield of germline testing....

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Identifiers

PMID: 37924330
DOI: 10.1001/jamaoncol.2023.5586
PMCID: PMC10625669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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