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Article

Assessment of Diagnostic Outcomes of RNA Genetic Testing for Hereditary Cancer.

JAMA network open - 2 Oct 2019

Karam Rachid, Conner Blair, LaDuca Holly, McGoldrick Kelly, Krempely Kate, Richardson Marcy E, Zimmermann Heather, Gutierrez Stephanie, Reineke Patrick, Hoang Lily, Allen Kyle, Yussuf Amal, Farber-Katz Suzette, Rana Huma Q, Culver Samantha, Lee John, Nashed Sarah, Toppmeyer Deborah, Collins Debra, Haynes Ginger, Pesaran Tina, Dolinsky Jill S, Tippin Davis Brigette, Elliott Aaron, Chao Elizabeth

Abstract excerpt

Importance: Performing DNA genetic testing (DGT) for hereditary cancer genes is now a well-accepted clinical practice; however, the interpretation of DNA variation remains a challenge for laboratories and clinicians. Adding RNA genetic testing (RGT) enhances DGT by clarifying the clinical actionability of hereditary cancer gene variants, thus improving clinicians' ability to accurately apply strategies for cancer...

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Identifiers

PMID: 31642931
DOI: 10.1001/jamanetworkopen.2019.13900
PMCID: PMC6820040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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