Article
Clinical integration of germline findings from a tumor testing precision medicine program.
BMC cancer - 30 Jan 2025
Sanabria-Salas Maria Carolina, Anggala Nina C, Gillies Brittany, Farncombe Kirsten M, Hofstedter Renee, Peck Larissa, Purnaghshband Helia, Redondo Laura, Thain Emily, Xu Wei, Sabatini Peter, Bedard Philippe L, Kim Raymond H
Abstract excerpt
BACKGROUND: Integrating germline genetic testing (GGT) recommendations from tumor testing into hereditary cancer clinics and precision oncology trials presents challenges that require multidisciplinary expertise and infrastructure. While there have been advancements in standardizing molecular tumor boards, the implementation of tumor profiling for germline-focused assessments has only recently gained momentum....
Read the complete abstract on PubMedTopics
- Humans
- Precision Medicine
- Germ-Line Mutation
- Genetic Testing
- Male
- Female