Article

Clinical Integration of Germline Findings from a Tumor Testing Precision Medicine Program

2024-11-11

Abstract excerpt

<title>Abstract</title> <p>Background: Integrating germline genetic testing (GGT) recommendations from tumor testing into hereditary cancer clinics and precision oncology trials presents challenges that require multidisciplinary expertise and infrastructure. While there have been advancements in standardizing molecular tumor boards, the implementation of tumor profiling for germline-focused assessments has only...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7c41fd52-da96-5af5-9bbe-766dfef58c9a
DOI: 10.21203/rs.3.rs-5290739/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Clinical Integration of Germline Findings from a Tumor Testing Precision Medicine ProgramDOI 10.21203/rs.3.rs-5290739/v1Read

Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories.Semantic proximity Read

Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers.Semantic proximity Read

Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome.Semantic proximity Read

Genetic Counseling and Germline Testing in the Era of Tumor Sequencing: A Cohort StudySemantic proximity Read

Consideration for Multigene Panel Testing Outside of Cancer-Specific Genetic Testing.Semantic proximity Read

Germline pathogenic variants identification through Comprehensive Cancer Genome ProfilingSemantic proximity Read

Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients.Semantic proximity Read

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.Semantic proximity Read

Assessing actionability and incidental findings of germline variants in two precision oncology trials.Semantic proximity Read

Prevalence of Germline Findings Among Tumors From Cancer Types Lacking Hereditary Testing Guidelines.Semantic proximity Read

Precision medicine in heritable cancer: when somatic tumour testing and germline mutations meetSemantic proximity Read

Germline Genetic Testing After Cancer DiagnosisSemantic proximity Read