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Article

The HIV-2 proviral landscape is dominated by defective proviruses

2 Nov 2023

Abstract excerpt

BACKGROUND: Compared with HIV-1 infection, HIV-2 infection is associated with a slower progression to AIDS. Understanding the persistence of HIV-2 infection might inform the mechanisms responsible for differences in the pathogenicity of HIV-2 versus HIV-1. METHODS: In this study, we analyzed the genetic composition of the proviral reservoir in archived blood samples collected from 13 untreated HIV-2-infected...

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PMID: 37916471
DOI: 10.1097/qad.0000000000003776

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