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Small-molecule inhibitors targeting FOXM1: Current challenges and future perspectives in cancer treatments

31 Oct 2023

Abstract excerpt

Forkhead box (FOX) protein M1 (FOXM1) is a critical proliferation-associated transcription factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also been implicated in poor prognosis. A comprehensive understanding of various aspects of this molecule has revealed its role in, cell proliferation, cell migration, invasion, angiogenesis and metastasis. The FOXM1 as a TF directly or...

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PMID: 37913940
DOI: 10.1016/j.bbcan.2023.189015

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