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Article

Role of RNA Alternative Splicing in T Cell Function and Disease

30 Sept 2023

Abstract excerpt

Alternative RNA splicing, a ubiquitous mechanism of gene regulation in eukaryotes, expands genome coding capacity and proteomic diversity. It has essential roles in all aspects of human physiology, including immunity. This review highlights the importance of RNA alternative splicing in regulating immune T cell function. We discuss how mutations that affect the alternative splicing of T cell factors can contribute...

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PMID: 37895245
DOI: 10.3390/genes14101896

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