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Article

Alternative Splicing: A New Cause and Potential Therapeutic Target in Autoimmune Disease.

Frontiers in immunology - 1 Jan 2021

Ren Pingping, Lu Luying, Cai Shasha, Chen Jianghua, Lin Weiqiang, Han Fei

Abstract excerpt

Alternative splicing (AS) is a complex coordinated transcriptional regulatory mechanism. It affects nearly 95% of all protein-coding genes and occurs in nearly all human organs. Aberrant alternative splicing can lead to various neurological diseases and cancers and is responsible for aging, infection, inflammation, immune and metabolic disorders, and so on. Though aberrant alternative splicing events and their...

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Source

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Identifiers

PMID: 34484216
DOI: 10.3389/fimmu.2021.713540
PMCID: PMC8416054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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