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Article

Alternative splicing in multiple sclerosis and other autoimmune diseases

1 Jul 2010

Abstract excerpt

Alternative splicing is a general mechanism for regulating gene expression that affects the RNA products of more than 90% of human genes. Not surprisingly, alternative splicing is observed among gene products of metazoan immune systems, which have evolved to efficiently recognize pathogens and discriminate between "self" and "non-self", and thus need to be both diverse and flexible. In this review we focus on the...

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PMID: 20639696
DOI: 10.4161/rna.7.4.12301

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