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Article

Understanding Arrhythmogenic Cardiomyopathy: Advances through the Use of Human Pluripotent Stem Cell Models.

Genes - 25 Sept 2023

Chua Christianne J, Morrissette-McAlmon Justin, Tung Leslie, Boheler Kenneth R

Abstract excerpt

Cardiomyopathies (CMPs) represent a significant healthcare burden and are a major cause of heart failure leading to premature death. Several CMPs are now recognized to have a strong genetic basis, including arrhythmogenic cardiomyopathy (ACM), which predisposes patients to arrhythmic episodes. Variants in one of the five genes (PKP2, JUP, DSC2, DSG2, and DSP) encoding proteins of the desmosome are known to cause...

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Share to Cardiac electrophysiology and arrhythmias
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37895213
DOI: 10.3390/genes14101864
PMCID: PMC10606441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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