Article
Insights Into Genetics and Pathophysiology of Arrhythmogenic Cardiomyopathy.
Current heart failure reports - 1 Dec 2021
Gerull Brenda, Brodehl Andreas
Abstract excerpt
PURPOSE OF REVIEW: Arrhythmogenic cardiomyopathy (ACM) is a genetic disease characterized by life-threatening ventricular arrhythmias and sudden cardiac death (SCD) in apparently healthy young adults. Mutations in genes encoding for cellular junctions can be found in about half of the patients. However, disease onset and severity, risk of arrhythmias, and outcome are highly variable and drug-targeted treatment is...
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