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Article

Molecular Mechanisms Provide a Landscape for Biomarker Selection for Schizophrenia and Schizoaffective Psychosis.

International journal of molecular sciences - 18 Oct 2023

Fryar-Williams Stephanie, Strobel Jörg, Clements Peter

Abstract excerpt

Research evaluating the role of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T) gene in schizophrenia has not yet provided an extended understanding of the proximal pathways contributing to the 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme's activity and the distal pathways being affected by its activity. This review investigates these pathways, describing mechanisms relevant to riboflavin...

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Identifiers

PMID: 37894974
DOI: 10.3390/ijms242015296
PMCID: PMC10607016

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