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Article

Gene Variant Related Neurological and Molecular Biomarkers Predict Psychosis Progression, with Potential for Monitoring and Prevention.

International journal of molecular sciences - 12 Dec 2024

Fryar-Williams Stephanie, Tucker Graeme, Clements Peter, Strobel Jörg

Abstract excerpt

The (MTHFR) C677T gene polymorphism is associated with neurological disorders and schizophrenia. Patients diagnosed with schizophrenia and schizoaffective disorder and controls (n 134) had data collected for risk factors, molecular and neuro-sensory variables, symptoms, and functional outcomes. Promising gene variant-related predictive biomarkers were identified for diagnosis by Receiver Operating Characteristics...

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PMID: 39769114
DOI: 10.3390/ijms252413348

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