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Article

Endothelial function, folate pharmacogenomics, and neurocognition in psychotic disorders.

Schizophrenia research - 1 May 2015

Grove Tyler, Taylor Stephan, Dalack Gregory, Ellingrod Vicki

Abstract excerpt

Cardiovascular disease (CVD) is a well-described complication of schizophrenia, however, mechanisms connecting CVD with other facets of psychotic disorders, such as neurocognition, are not understood. The current study examined folate metabolism as a potential mechanism of CVD and neurocognitive deficits by: 1) using endothelial dysfunction as a biomarker of CVD, and 2) comparing enzymes associated with...

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Source

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Identifiers

PMID: 25728832
DOI: 10.1016/j.schres.2015.02.006
PMCID: PMC4409513

Genes

COMT
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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