Article
Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case-control study.
BMC immunology - 22 Feb 2015
Hu Yi, Wu Linlin, Li Dange, Zhao Qi, Jiang Weili, Xu Biao
Abstract excerpt
BACKGROUND: Polymorphisms in cytokine genes are known to influence cytokine levels, which may influence susceptibility to tuberculosis (TB) infection and disease. Differences in cytokine expression probably determine whether TB progresses, resolves, or becomes latent. In particular, the balance between the Th1 and Th2 cytokine responses influences the expression of disease in individuals with pulmonary TB (PTB)....
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