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Cryptococcus gattii strains with a high phagocytosis phenotype by macrophages display high pathogenicity at the early stage of infection in vivo.

Acta biochimica et biophysica Sinica - 25 Feb 2024

Yang Chen, Shen Wanjun, Wang Lifeng, Zang Xuelei, Huang Yemei, Deng Hengyu, Zhou Yangyu, Xie Mei, Xue Xinying, Shen Dingxia

Abstract excerpt

Cryptococcus gattii (Cg) is a facultative intracellular pathogen that can replicate and disseminate in mammalian macrophages, causing life-threatening cryptococcosis in both immunocompetent and immunocompromised individuals. Cryptococcus-macrophage interactions are crucial for cryptococcosis prognosis. However, the relationship between Cg pathogenicity and phagocytosis by macrophages has not yet been investigated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37885429
DOI: 10.3724/abbs.2023250
PMCID: PMC10984874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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