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Article

Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii

13 Apr 2018

Abstract excerpt

The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life-threatening fungal infections in otherwise healthy human hosts currently known. The outbreak lineage has a remarkable ability to grow rapidly within human white blood cells, using a unique 'division of labour' mechanism within the pathogen...

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PMID: 29674675
DOI: 10.1038/s41467-018-03991-6

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