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Article

Influence of sex on the exposure to isoniazid in patients with pulmonary tuberculosis.

Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2023

Rivera Juan Gonzalo Bardalez, Albério Carlos Augusto Abreu, Vieira José Luiz Fernandes

Abstract excerpt

Isoniazid is a key component of tuberculosis treatment. Adequate exposure is a determinant for therapeutic success; however, considerable inter- and intraindividual variations in drug plasma levels can lead to unfavorable outcomes. While some predictors of isoniazid levels are well-known, others, such as sex, yield controversial results, requiring further investigation to optimize exposure. This study...

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Identifiers

PMID: 37878973
DOI: 10.1590/S1678-9946202365056
PMCID: PMC10588987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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