Article
Evolution of haploid and diploid populations reveals common, strong, and variable pleiotropic effects in non-home environments.
eLife - 20 Oct 2023
Chen Vivian, Johnson Milo S, Hérissant Lucas, Humphrey Parris T, Yuan David C, Li Yuping, Agarwala Atish, Hoelscher Samuel B, Petrov Dmitri A, Desai Michael M, Sherlock Gavin
Abstract excerpt
Adaptation is driven by the selection for beneficial mutations that provide a fitness advantage in the specific environment in which a population is evolving. However, environments are rarely constant or predictable. When an organism well adapted to one environment finds itself in another, pleiotropic effects of mutations that made it well adapted to its former environment will affect its success. To better...
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