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Applicability of the FDA-approved Immunohistochemical Panel for Identification of MMRd Phenotype in Uterine Endometrioid Carcinoma.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2024

Adachi Sumiyo, Kimata Jun-Ichiro, Hanami Kyota, Adachi Katsuyuki, Igarashi Toshio, Liang Shan-Guang, Ishida Yasuo, Fujino Takashi, Yamazaki Kazuto

Abstract excerpt

Recently, the US Food and Drug Administration (FDA) approved the Ventana MMR RxDx Panel as the first immunohistochemical companion diagnostic test for identification of tumors with mismatch repair (MMR) status. The aim of this study was to investigate the accuracy of this test in comparison with polymerase chain reaction (PCR)-based microsatellite instability (MSI) analysis. We assessed the MMR/MSI concordance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37859432
DOI: 10.1097/PAI.0000000000001170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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