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Article

Repeated local ellipsoid protrusion supplements HLA surface characterization.

HLA - 1 Jan 2024

Niemann Matthias, Matern Benedict M, Spierings Eric

Abstract excerpt

Allorecognition of donor HLA is a major risk factor for long-term kidney graft survival. Although several molecular matching algorithms have been proposed that compare physiochemical and structural features of the donors' and recipients' HLA proteins in order to predict their compatibility, the exact underlying mechanisms are still not fully understood. We hypothesized that the ElliPro approach of single...

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PMID: 37853578
DOI: 10.1111/tan.15260

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