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Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation

28 Oct 2022

Abstract excerpt

Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ donor's HLA proteins. Matching donors and recipients based on HLA epitopes appears beneficial for the avoidance of DSA. Defining surface epitopes however remains...

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PMID: 36389845
DOI: 10.3389/fimmu.2022.1005601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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