Article
Association Study Confirmed Three Breast Cancer-Specific Molecular Subtype-Associated Susceptibility Loci in Chinese Han Women.
The oncologist - 1 Aug 2017
Xu Yihui, Chen Mengyun, Liu Chenchen, Zhang Xiaowei, Li Wei, Cheng Huaidong, Zhu Jun, Zhang Mingjun, Chen Zhendong, Zhang Bo
Abstract excerpt
BACKGROUND: Breast cancer is a heterogeneous and polygenic disease that can be divided into different molecular subtypes based on histological and genomic features. To date, numerous susceptibility loci of breast cancer have been discovered by genome-wide association studies and may expand the genetic features. However, few loci have been further studied according to molecular subtypes. MATERIALS AND METHODS: We...
Topics
- Adult
- Aged
- Breast Neoplasms
- China
- Female
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- Humans
- MAP Kinase Kinase Kinase 1
- Middle Aged