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Article

Chemical carcinogens: implications for cancer treatment.

The Journal of clinical investigation - 16 Oct 2023

Liu Shaofeng, Saunders Mary, Mak Tak W

Abstract excerpt

Carcinogen exposure has been associated with enhanced cancer immunogenicity that is often attributed to neoantigen generation. However, the broader, neoantigen-independent impact of carcinogens on immune responses to cancer cells remains underexplored. In this issue of the JCI, Huang et al. uncover a mechanism wherein carcinogen-treated cancer cells exhibit an inability to establish an immunosuppressive tumor...

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Source

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Identifiers

PMID: 37843275
DOI: 10.1172/JCI174319
PMCID: PMC10575717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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