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Article

Silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment.

Neoplasia (New York, N.Y.) - 1 Aug 2013

Freire Javier, Ajona Daniel, de Biurrun Gabriel, Agorreta Jackeline, Segura Victor, Guruceaga Elizabeth, Bleau Anne-Marie, Pio Ruben, Blanco David, Montuenga Luis M

Abstract excerpt

The association between inflammation and lung tumor development has been clearly demonstrated. However, little is known concerning the molecular events preceding the development of lung cancer. In this study, we characterize a chemically induced lung cancer mouse model in which lung cancer develo...

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Source

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Identifiers

PMID: 23908592
DOI: 10.1593/neo.13310
PMCID: PMC3730043

Genes

FOXP3
LAG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23908592-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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