Article
Estrogen receptor and breast cancer.
Seminars in cancer biology - 1 Oct 2001
Sommer S, Fuqua S A
Abstract excerpt
Breast cancer, the most common malignancy in women, was already known to be associated with the steroid hormone estrogen more than a century ago. The discovery of the estrogen receptor (ER) provided us not only with a powerful predictive and prognostic marker, but also an efficient target for the treatment of hormone-dependent breast cancer with antiestrogens. In this paper we will sketch the important role of ER...
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