Article
Genetic Variants in WNT16 and PKD2L1 Locus Affect Heel Ultrasound Bone Stiffness: Analyses from the General Population and Patients Evaluated for Osteoporosis.
Calcified tissue international - 1 Nov 2023
Kragl Angelique, Hannemann Anke, Nauck Matthias, Völker Uwe, Siggelkow Heide, Teumer Alexander, Tzvetkov Mladen V
Abstract excerpt
Osteoporosis, a complex chronic disease with increasing prevalence, is characterised by reduced bone mineral density (BMD) and increased fracture risk. The high heritability of BMD suggests substantial impact of the individual genetic disposition on bone phenotypes and the development of osteoporosis. In the past years, genome-wide association studies (GWAS) identified hundreds of genetic variants associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
