Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of PIEZO1 polymorphisms for human bone mineral density.

Bone - 1 Apr 2020

Bai Wei-Yang, Wang Lijun, Ying Zhi-Min, Hu Bin, Xu Lin, Zhang Guo-Qing, Cong Pei-Kuan, Zhu Xiaofeng, Zou Weiguo, Zheng Hou-Feng

Abstract excerpt

Bone mineral density (BMD) is a key indicator for diagnosis and treatment for osteoporosis; the reduction of BMD could increase the risk of osteoporotic fracture. It was very recently found that Piezo1 mediated mechanically evoked responses in bone and further participated in bone formation in mice. Here, we performed cross phenotype meta-analysis for human BMD at lumbar spine (LS), femoral neck (FN), distal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Femur Neck
Share to Ion Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lumbar Vertebrae

Share to Osteoporosis

Share to Osteoporotic Fractures

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 31968281
DOI: 10.1016/j.bone.2020.115247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of PIEZO1 polymorphisms for human bone mineral density.PMID 31968281Read ↗

Identification of Key Genes and Pathways Associated with PIEZO1 in Bone-Related Disease Based on BioinformaticsSemantic proximity Read ↗

PIEZO1 variant implications for biological understanding and human healthSemantic proximity Read ↗

The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performanceSemantic proximity Read ↗

An Atlas of Human and Murine Genetic Influences on OsteoporosisSemantic proximity Read ↗

Roles of mechanosensitive channel Piezo1/2 proteins in skeleton and other tissuesSemantic proximity Read ↗

Mechanoepigenetics in musculoskeletal disease.Semantic proximity Read ↗

Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.Semantic proximity Read ↗

The role of PIEZO ion channels in the musculoskeletal systemSemantic proximity Read ↗

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.Semantic proximity Read ↗

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.Semantic proximity Read ↗

Analysis of SNP-SNP interactions and bone quantitative ultrasound parameter in early adulthood.Semantic proximity Read ↗

PIEZO1-mediated mechanosensation links aging to bladder dysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.