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Article

Impact of family history on choosing risk-reducing surgery among BRCA mutation carriers.

American journal of obstetrics and gynecology - 1 Apr 2013

Singh Krishna, Lester Jenny, Karlan Beth, Bresee Catherine, Geva Tali, Gordon Ora

Abstract excerpt

OBJECTIVE: Despite substantial survival benefits of risk-reducing mastectomy (RRM) and risk-reducing bilateral salpingo-oophorectomy (RRBSO) among BRCA mutation carriers, only a minority elect to undergo these procedures. This study investigates factors that might influence decision making regarding prophylactic surgeries among women with BRCA mutations. STUDY DESIGN: Unaffected BRCA mutation carriers who were...

Topics

Adult
Breast Neoplasms
Choice Behavior
Family Health
Female
Genes, BRCA1
Genes, BRCA2
Heterozygote
Humans
Mastectomy
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovarian Neoplasms

Ovariectomy

Risk Reduction Behavior

Source

Identifiers

PMID: 23333547
DOI: 10.1016/j.ajog.2013.01.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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