Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Dec 1996

Grantham J J

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in at least three different genes: PKD1, PKD2, and PKD3. ADPKD1 is an inherited disorder that has led to the discovery of a novel protein, polycystin. Polycystin, a 460 kd protein with a host of domains implicating a pote...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Fluids
Share to Chlorides
Share to Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PKD1 gene

Share to Kidney Tubules

Share to Mutation

Share to Polycystic Kidney, Autosomal Dominant

Share to Proteins

Source

Identifiers

PMID: 8957030
DOI: 10.1016/s0272-6386(96)90378-9

Genes

PKD2
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8957030-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances.PMID 8957030Read ↗

Autosomal dominant polycystic kidney disease: Disrupted pathways and potential therapeutic interventions.Semantic proximity Read ↗

Treatment of autosomal dominant polycystic kidney disease (ADPKD): the new horizon for children with ADPKD.Semantic proximity Read ↗

Kidney: polycystic kidney diseaseSemantic proximity Read ↗

Autosomal dominant polycystic kidney disease: clues to pathogenesis.Semantic proximity Read ↗

Genetics and Pathogenesis of Polycystic Kidney DiseaseSemantic proximity Read ↗

Molecular pathogenesis of ADPKD: the polycystin complex gets complex.Semantic proximity Read ↗

Molecular and cellular pathogenesis of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy.Semantic proximity Read ↗

New insights into polycystic kidney disease and its treatment.Semantic proximity Read ↗

The polycystins: a novel class of membrane-associated proteins involved in renal cystic disease.Semantic proximity Read ↗

[Pathophysiology, epidemiology, clinical presentation, diagnosis and treatment options for autosomal dominant polycystic kidney disease].Semantic proximity Read ↗

Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.