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Mitochondrial SOS: how mtDNA may act as a stress signal in Alzheimer’s disease

11 Oct 2023

Abstract excerpt

BACKGROUND: Alterations in mitochondrial DNA (mtDNA) levels have been observed in Alzheimer's disease and are an area of research that shows promise as a useful biomarker. It is well known that not only are the mitochondria a key player in producing energy for the cell, but they also are known to interact in other important intracellular processes as well as extracellular signaling and communication. BODY: This...

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PMID: 37821944
DOI: 10.1186/s13195-023-01322-6

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