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Article

Genetic determinants underlying the progressive phenotype of β-lactam/β-lactamase inhibitor resistance in Escherichia coli.

Microbiology spectrum - 12 Dec 2023

Shropshire William C, Amiji Hatim, Bremer Jordan, Selvaraj Anand Selvalakshmi, Strope Benjamin, Sahasrabhojane Pranoti, Gohel Marc, Aitken Samuel, Spitznogle Sarah, Zhan Xiaowei, Kim Jiwoong, Greenberg David E, Shelburne Samuel A

Abstract excerpt

IMPORTANCE: The increased feasibility of whole-genome sequencing has generated significant interest in using such molecular diagnostic approaches to characterize difficult-to-treat, antimicrobial-resistant (AMR) infections. Nevertheless, there are current limitations in the accurate prediction of AMR phenotypes based on existing AMR gene database approaches, which primarily correlate a phenotype with the...

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PMID: 37800937
DOI: 10.1128/spectrum.02221-23
PMCID: PMC10715226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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