Article
Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli: an observational study.
The Lancet. Microbe - 1 Nov 2025
Lipworth Samuel, Chau Kevin, Oakley Sarah, Barrett Lucinda, Crook Derrick, Peto Tim, Walker A Sarah, Stoesser Nicole
Abstract excerpt
BACKGROUND: Surveillance and prediction of antibiotic resistance in Escherichia coli relies on curated databases of genes and mutations. We aimed to quantify the effect of acquiring specific genetic elements on minimum inhibitory concentrations (MICs) for particular antibiotic-species combinations, addressing the current scarcity of such data in existing databases. METHODS: For this observational study, we...
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