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Toward Informed Selection and Interpretation of Clinical Genomic Tests in Prostate Cancer

1 Mar 2024

Abstract excerpt

Clinical genomic testing of patient germline, tumor tissue, or plasma cell-free DNA can enable a personalized approach to cancer management and treatment. In prostate cancer (PCa), broad genotyping tests are now widely used to identify germline and/or somatic alterations in BRCA2 and other DNA damage repair genes. Alterations in these genes can confer cancer sensitivity to poly (ADP-ribose) polymerase inhibitors,...

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PMID: 38547422
DOI: 10.1200/po.23.00654

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