Challenges of diagnosing homologous recombination deficiencies in metastatic prostate cancer: a six-year experience from a single institution.

doi:10.1007/s12094-024-03483-8

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Article

Challenges of diagnosing homologous recombination deficiencies in metastatic prostate cancer: a six-year experience from a single institution.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Oct 2024

Gavira Javier, Tapia Jose Carlos, Romano Alejandra, Anguera Georgia, Aguado María, Piedra Aida, Bosma Freya, Sánchez Sofía, Martin Cristina, Algaba Ferran, Arce Yolanda, Ramón Y Cajal Teresa, Maroto Pablo

Abstract excerpt

PURPOSE: We evaluated the prevalence of homologous recombination deficiencies (HRD) to determine the efficacy of different techniques and clinical characteristics of patients. METHODS: This retrospective study included patients with metastatic prostate cancer who underwent molecular testing at our hospital between 2016 and 2022. We used tumor tissue, ctDNA, and lymphocytes for somatic or germline testing. We...

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PMID: 38722534
DOI: 10.1007/s12094-024-03483-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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