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The Drosophila melanogaster prophenoloxidase system participates in immunity against Zika virus infection

4 Oct 2023

Abstract excerpt

Drosophila melanogaster relies on an evolutionarily conserved innate immune system to protect itself from a wide range of pathogens, making it a convenient genetic model to study various human pathogenic viruses and host antiviral immunity. Here we explore for the first time the contribution of the Drosophila phenoloxidase (PO) system to host survival and defenses against Zika virus (ZIKV) infection by analyzing...

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PMID: 37793051
DOI: 10.1002/eji.202350632

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