Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression

Abstract excerpt

Drosophila melanogaster has one of the best characterized antiviral immune responses among invertebrates. However, relatively few easily transmitted natural virus isolates are available, and so many Drosophila experiments have been performed using artificial infection routes and artificial host–virus combinations. These may not reflect natural infections, especially for subtle phenotypes such as gene expression....

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