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Article

Prophenoloxidase activation is not required for survival to microbial infections in Drosophila.

EMBO reports - 1 Feb 2006

Leclerc Vincent, Pelte Nadège, El Chamy Laure, Martinelli Cosimo, Ligoxygakis Petros, Hoffmann Jules A, Reichhart Jean-Marc

Abstract excerpt

The antimicrobial defence of Drosophila relies on cellular and humoral processes, of which the inducible synthesis of antimicrobial peptides has attracted interest in recent years. Another potential line of defence is the activation, by a proteolytic cascade, of phenoloxidase, which leads to the production of quinones and melanin. However, in spite of several publications on this subject, the contribution of...

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Identifiers

PMID: 16322759
DOI: 10.1038/sj.embor.7400592
PMCID: PMC1369246

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Source receipt: pubmed, retrieved 7 Sept 2026.

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