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Article

scQTLbase: an integrated human single-cell eQTL database.

Nucleic acids research - 5 Jan 2024

Ding Ruofan, Wang Qixuan, Gong Lihai, Zhang Ting, Zou Xudong, Xiong Kewei, Liao Qi, Plass Mireya, Li Lei

Abstract excerpt

Genome-wide association studies (GWAS) have identified numerous genetic variants associated with diseases and traits. However, the functional interpretation of these variants remains challenging. Expression quantitative trait loci (eQTLs) have been widely used to identify mutations linked to disease, yet they explain only 20-50% of disease-related variants. Single-cell eQTLs (sc-eQTLs) studies provide an immense...

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Share to Databases, Genetic
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

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Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 37791879
DOI: 10.1093/nar/gkad781
PMCID: PMC10767909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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