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Article

An alpha-helix variant p.Arg156Pro in LMNA as a cause of hereditary dilated cardiomyopathy: genetics and bioinfomatics exploration.

BMC medical genomics - 2 Oct 2023

Chang Lei, Huang Rong, Chen Jianzhou, Li Guannan, Shi Guangfei, Xu Biao, Wang Lian

Abstract excerpt

LMNA gene encodes lamin A/C protein which participates in the construction of nuclear lamina, the mutations of LMNA result in a wide variety of diseases known as laminopathies. LMNA-related dilated cardiomyopathy(LMNA-DCM) is one of the more common laminopathy which characterized by progressive heart failure and arrhythmia. However, the mutation features of LMNA-DCM are yet to be elucidated. Herein we described a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Conformation, alpha-Helical

Source

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Identifiers

PMID: 37784143
DOI: 10.1186/s12920-023-01661-1
PMCID: PMC10544607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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