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Article

Identification of mutational hot spots in LMNA encoding lamin A/C in patients with familial dilated cardiomyopathy.

Basic research in cardiology - 1 Jan 2009

Perrot Andreas, Hussein Shwan, Ruppert Volker, Schmidt Hartmut H J, Wehnert Manfred S, Duong Nguyen Thuy, Posch Maximilian G, Panek Anna, Dietz Rainer, Kindermann Ingrid, Böhm Michael, Michalewska-Wludarczyk Aleksandra, Richter Anette, Maisch Bernhard, Pankuweit Sabine, Ozcelik Cemil

Abstract excerpt

The familial form of dilated cardiomyopathy (DCM) occurs in about 20%-50% of DCM cases. It is a heterogeneous genetic disease: mutations in more than 20 different genes have been shown to cause familial DCM. LMNA, encoding the nuclear membrane protein lamin A/C, is one of the most important disea...

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Identifiers

PMID: 18795223
DOI: 10.1007/s00395-008-0748-6

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18795223-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Identification of mutational hot spots in LMNA encoding lamin A/C in patients with familial dilated cardiomyopathy.PMID 18795223Read ↗

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